15811039 原AZD 4017、1024033-43-9 制造商,库存 398g,含量 98.65%

CAS 1024033-43-9: AZD4017

  • CAS 1024033-43-9: AZD4017

CAS 1024033-43-9: AZD4017
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  • CAS Number: 1024033-43-9
  • Stock: 398g
  • Assay: 98.65%

AZD4017, CAS 1024033-43-9

AZD4017, CAS 1024033-43-9, 库存 498g, 含量 99.7%, 白色粉末, 水 0.29%, 单杂 0.3%.


AZD4017

AZD4017 是一种有效的、选择性的、口服生物可利用的 11β-HSD1 抑制剂(11β-羟基类固醇脱氢酶 1 型抑制剂)。 抑制 11β-HSD1 是治疗肥胖和代谢综合征其他因素的一种有吸引力的机制。 AZD4017 是一种烟酰胺衍生的羧酸类抑制剂,具有良好的效力、选择性和药代动力学特征。 AZD4017) 是人类脂肪细胞中 11β-HSD1 的有效抑制剂,具有良好的药物特性,因此被选择用于临床开发。


产品详情:

名称: AZD4017

CAS#: 1024033-43-9

化学式: C22H33N3O3S

精准质量: 419.22426

分子量: 419.58

元素分析: C, 62.98; H, 7.93; N, 10.01; O, 11.44; S, 7.64


规格:

Synonym: AZD4017; AZD-4017; AZD 4017.


IUPAC/Chemical Name: 2-[(3S)-1-[5-(cyclohexylcarbamoyl)-6-propylsulfanylpyridin-2-yl]-3-piperidyl]acetic acid


InChi Key: NCDZABJPWMBMIQ-INIZCTEOSA-N


InChi Code: InChI=1S/C22H33N3O3S/c1-2-13-29-22-18(21(28)23-17-8-4-3-5-9-17)10-11-19(24-22)25-12-6-7-16(15-25)14-20(26)27/h10-11,16-17H,2-9,12-15H2,1H3,(H,23,28)(H,26,27)/t16-/m0/s1


SMILES Code: O=C(O)C[C@H]1CN(C2=NC(SCCC)=C(C(NC3CCCCC3)=O)C=C2)CCC1


Appearance: Solid powder


Purity: >99% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

HS Tariff Code: 2934.99.9001


Certification: