EX-527(R), CAS 848193-69-1
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- CAS Number: 848193-69-1
- Stock： 781g
- Assay: 98.64%
EX-527(R), CAS 848193-69-1
EX-527(R), CAS 848193-69-1, 库存 781g, 含量 98.64%, 白色粉末, 水分 0.24%, 单一杂质0.32%.
EX-527(R)
(R)-Selisistat，也称为 EX-527(R)，是一种选择性 SIRT1 抑制剂。 Sirt1 是一种高度保守的烟酰胺腺嘌呤二核苷酸 (NAD(+)) 依赖性组蛋白脱乙酰酶，在心脏病中起重要作用。
产品详情:
名称：(R)-Seliistat
CAS#: 848193-69-1 (R-异构体)
化学式：C13H13ClN2O
精确质量：248.0716
分子量：248.71
元素分析: C, 62.78; H, 5.27; Cl, 14.25; N, 11.26; O, 6.43
规格:
相关 CAS #: 848193-69-1 (R-异构体) 848193-68-0 (S-异构体) 49843-98-3 (外消旋体)
同义词：(R)-Seliistat; EX-527(R)； EX 527(R)； EX527(R);
IUPAC/化学名称：(R)-6-Chloro-2,3,4,9-四氢-1H-咔唑-1-甲酰胺
InChi Key：FUZYTVDVLBBXDL-SECBINFHSA-N
InChi代码：InChI=1S/C13H13ClN2O/c14-7-4-5-11-10(6-7)8-2-1-3-9(13(15)17)12(8)16-11/h4 -6,9,16H,1-3H2,(H2,15,17)/t9-/m1/s1
SMILES代码：O=C([C@H]1C(NC2=C3C=C(Cl)C=C2)=C3CCC1)N
外观：白色粉末
纯度：>98%（或参考分析证书）
运输条件：在环境温度下作为非危险化学品运输。该产品在普通运输和在海关停留的时间里足够稳定几周。
储存条件：干燥、黑暗，短期（数天至数周）或 -20 C 的长期（数月至数年）在 0 - 4 C 下。
溶解性：溶于DMSO
保质期：如果储存得当，>2 年
药物配方：该药物可在 DMSO 中配制
原液储存：短期（数天到数周）0 - 4 C，长期（数月）-20 C。
HS 关税代码：2934.99.9001
指标:
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EX-527(R), CAS 848193-69-1
EX-527(R), CAS 848193-69-1, Stock 781g, Assay 98.64%, White powder, Water 0.24%, Single Impurity 0.32%.
EX-527(R)
(R)-Selisistat, also known as EX-527(R), is a selective SIRT1 inhibitor. Sirt1 is a highly conserved nicotinamide adenine dinucleotide (NAD(+)) dependent histone deacetylase which plays an important role in heart diseases.
Product Details:
Name: (R)-Selisistat
CAS#: 848193-69-1 (R-isomer)
Chemical Formula: C13H13ClN2O
Exact Mass: 248.0716
Molecular Weight: 248.71
Elemental Analysis: C, 62.78; H, 5.27; Cl, 14.25; N, 11.26; O, 6.43
Specification:
Related CAS #: 848193-69-1 (R-isomer) 848193-68-0 (S-isomer) 49843-98-3 (racemate)
Synonym: (R)-Selisistat; EX-527(R); EX 527(R); EX527(R);
IUPAC/Chemical Name: (R)-6-Chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide
InChi Key: FUZYTVDVLBBXDL-SECBINFHSA-N
InChi Code: InChI=1S/C13H13ClN2O/c14-7-4-5-11-10(6-7)8-2-1-3-9(13(15)17)12(8)16-11/h4-6,9,16H,1-3H2,(H2,15,17)/t9-/m1/s1
SMILES Code: O=C([C@H]1C(NC2=C3C=C(Cl)C=C2)=C3CCC1)N
Appearance: White powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
Certification: